I'm having the same issue but with Windows 8 x64 Installed it and re installed is several time and but when i open it, it asks for admin permissions then doesn't open I tried to start in in compatibility mode for Windows XP and 7 and still no luck.
system specs: Dell vostro 1500 Core 2 Duo T8300 2.4GHz 4GB DDR2 Windows 8 Release Preview
First off I for the life of me can not find on this site, the FAQ, except of the one for the forums. Second I have been using DVD Shrink since its infancy and I am just now having issues with in in regards to some Windows 7 and some Windows 8 machines. I have also been able to use it in Linux under WINE with very little issue, but this one stumps me.